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LSU vs. Ole Miss Odds

Lane Kiffin has steadily built up Ole Miss as a football program since taking the head coaching job in 2020. The Rebels have decisively won most of their games, boasting the 15th-ranked offense and equally potent defense. Kentucky nearly ruined Ole Miss’ undefeated season back on October 1, but a strong fourth quarter from the defense kept the Rebels in the win column.

LSU is attempting to do the same with its program after sacking former head coach Ed Orgeron in favor of Brian Kelly. The Tigers had a rocky start to the season, scoring what should have been the equalizing touchdown against Florida State to send the game to overtime. However, a blocked extra-point attempt disappointingly ended the game. The Tigers were small home underdogs against Tennessee in Week 6, but it went south quickly, resulting in a lopsided 40-13 loss.

Can transfer quarterback Jayden Daniels score six more touchdowns as he did in a 45-35 win over Florida in Week 7?

LSU vs. Ole Miss Start Time and Where to Watch

Date: Saturday, October 22

Game time: 3:30 p.m. ET

Where to Watch: CBS

LSU vs. Ole Miss Odds

Spread: Ole Miss +1.5 (-110), LSU -1.5 (-110)

Total: Under 66.5 (-110), Over 66.5 (-110)

Moneyline: Ole Miss (+105), LSU (-125)